What is a common underlying cause of Cor Pulmonale?

Cor Pulmonale specifically refers to right heart failure that is secondary to chronic respiratory conditions, most notably chronic obstructive pulmonary disease (COPD). This condition leads to a decrease in oxygenation in the blood and results in increased pressure in the pulmonary arteries as the body attempts to overcome the impaired gas exchange. Over time, this increased pressure places a significant strain on the right ventricle of the heart, ultimately leading to its enlargement and failure.

Chronic obstructive pulmonary disease is characterized by airflow limitation and can include conditions such as emphysema and chronic bronchitis, which ultimately cause long-term respiratory problems. As the lung function declines, the right side of the heart must work harder to pump blood through the pulmonary arteries, leading to the development of Cor Pulmonale.

Understanding that Cor Pulmonale arises primarily from respiratory conditions helps in managing and treating the underlying cause, such as COPD, as opposed to focusing solely on cardiovascular issues that may not address the root problem.