What condition is characterized by right ventricular enlargement caused by pulmonary hypertension?

Cor Pulmonale is specifically defined as the alteration of the structure and function of the right ventricle due to a primary disorder of the respiratory system, leading to pulmonary hypertension. In cases where there is elevated pressure in the pulmonary artery, the right ventricle has to work harder to pump blood into the lungs, which can lead to right ventricular hypertrophy and eventually right heart failure if the underlying pulmonary condition is not managed.

This condition typically arises from chronic respiratory issues, such as chronic obstructive pulmonary disease (COPD) or pulmonary fibrosis, but can also result from any situation that leads to elevated pressures in the pulmonary circulation. The hallmark symptom complex associated with cor pulmonale includes exertional dyspnea, fatigue, and eventual signs of right heart failure, such as edema and elevated jugular venous pressure.

The other conditions listed do not specifically relate to the same mechanism of right ventricular enlargement due to pulmonary hypertension. Myocardial infarction primarily concerns the heart muscle's blood supply and does not directly relate to right ventricular strain caused by lung-related issues. Atrial fibrillation is an arrhythmia that can develop as a consequence of various heart conditions but is not directly caused by pulmonary hypertension. Heart valve disease involves structural abnormalities in the heart